The balance between elimination and retention
The focus to date in convective therapies has been the efficient elimination of uremic toxins. Especially the subgroup of middle molecules is point of medical and scientific discussion. However, attention must also be drawn to various substances that should be retained e.g. proteins such as serum albumin.
Importance of Serum Albumin
Marker for nutritional and inflammatory status of maintenance dialysis patients.1
Strong predictor for mortality2
Highlights
References:
1 Clinical practice guidelines for nutrition in chronic renal failure. K/DOQI, National Kidney Foundation. Am Journal J Kidney Dis. 2000 Jun;35(6 Suppl 2):S1-140
2 Kalantar-Zadeh K et al.; Revisiting mortality predictability of serum albumin in the dialysis population: time dependency, longitual changes and population-attributable fraction, Nephrol Dial Transplant. 2005 Sep;20(9):1880-8.