Scientific evidence

Observing Albumin removal during HDF

The  elimination of uremic toxins as well as the albumin removal varies with different dialyzer, HDF conditions and patient population.^1,2

xevonta allows an highly efficient elimination of middle molecules and other uremic toxins, but restricts the loss of serum-albumin to 1.1±0.2 g/session for xevonta with the largest surface area of 2.3 m² when used under post-dilution HDF conditions using high convective volumes³. 

^References

^{1 Le Roy F, Hanoy M, Bertrand D, Freguin C, Grange S, Godin M. Dépuration de la Beta2-microglobuline et pertes dálbumine en HDF post-dilution: effect membrane. EDTA 2009}

^{2 Maduell et al.; Elimination of Large Uremic Toxins by a Dialyzer Specifically Designed for High-Volume Convective Therapies Blood Purif 2014;37:125–130}

^{3 Gayrard N et al. Influence of high convection volumes in removal performances of on-line haemodiafiltration (HDF). Nephrol. Dial. Transplant. (2013) 28 (suppl 1): i30-i32.}