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Semi-automated compounding
Gri-fill® 4
Gri-fill® 4 is a semi-automatic compounding system engineered for drug reconstitution and preparation of IV medications. Gri-fill® 4 efficiently fills IV bags, syringes, cassettes, and elastomeric devices, including B. Braun’s elastomeric pump: Easypump® II. Ideal for both batch and patient-specific production, Gri-fill® 4 is designed to handle hazardous and non-hazardous compounded sterile preparations. The entire process of drug reconstitution and container filling is seamlessly integrated into one streamlined operation.
Options for oncology
CIVAS / MABS Preparation
Gri-fill® 4 is compatible with closed system transfer devices (CSTD’s), including ChemfortTM which has been scientifically proven to help protect healthcare professionals when exposed to hazardous drugs.1,2,3
ChemfortTMOptions for OPAT
Antibiotics
Gri-fill® 4 supports pharmacy preparation of antibiotics in OPAT pathways helping to support aseptic efficiencies and output.
Manual filling of elastomeric devices, whether by hand or using an elastomeric handfiller, can be labour-intensive and increases risk of repetitive strain injury (RSI). Gri-fill® 4 helps reduce these issues, by promoting a semi-automatic process in pharmacy.
OPAT Pathway
Gri-fill® 4 Characteristics
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Source solution 1
Customisable to different source solutions including bag, bottle, and vials
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Benefits
- Lot traceability, expiration control and full audit trail of preparation process and user changes, ensuring regulatory compliance and efficient recall management
- Ensuring compliance through accurate reporting of preparation and wastage volumes
- Ease of use through mitigation of repetitive stress and needle-stick injuries associated with manual filling
- Doses from one or two source solutions, reconstitutes the vial and withdraws it from the final container
- Template options to print patient-specific and batch labels for preparations
- Air bubble detection feature
Dedicated Accessories
Dedicated accessory for filling via the volumetric pump pre-assembled with syringe and waste bag for efficient set up.
Dedicated accessory for filling with the peristaltic pump
Bag with a 0.2 filter to maintain sterility throughout the compounding process.
Available in sizes: 100mL, 250mL, 500mL and 1000mL
Allows the connection of six liquid vials of the same concentration.
- Creates a single virtual pooled container
- Use for reconstitution and dosing of up to six vials [optional]
Web-based software to manage production of up to five Gri-fill’s, facilitating optimal management of preparation orders.
1. P. Sessink et al., Validation of chemotherapy drug vapor containment of an air cleaning closed system drug transfer device, Journal of Oncology Pharmacy Practice, 2022 Oct; 28(7): 1508-1515
2. Wilkinson A.S., Allwood M.C., et al., Performance testing protocol for closed-system transfer devices used during pharmacy compounding and administration of hazardous drugs. PLoS ONE 13(10) : e0205263, Oct 2018
3. Chemfort data on file, Study 189, March 2018