SeQuent® Please vs. DES (EES) in de novo lesions

Key findings

In the DCB group, not a single case of TLR reported (0.0 %), in contrast to the DES group with a TLR rate of 6.1 % at 8-month follow-up. The authors conclude that “stent-less” PCI could be useful with regards to the reduction of DAPT and a discontinuation of DAPT than after DES implantation.

Description

Design: Randomised | Open-label | Prospective | Single centre

Indication: De novo

Primary endpoint: TLR @ 8-month follow-up

Secondary endpoint: LLL @ 8-month follow-up

Results

Patients: 60 consecutive patients were enrolled in this trial and randomised into the DCB or DES group. After lesion preparation with NSE Alpha, three patients in the DCB group had an unacceptable angiographic result and were moved into the DES group. Therefore, a total of 27 patients were in the DCB group, 33 patients in the DES group.

Baseline characteristics: The two treatment groups were well-balanced, there were no statistically significant differences between the two treatment groups.

Primary endpoint:

Secondary endpoint: