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Neurosurgery

Dura substitution

Fast. Easy. Versatile. Reliable.

Biological and synthetic dura substitutes

Dura substitutes are used to cover holes in the cerebral / cerebellar and spinal dura mater to restore a liquid-tight closure after neurosurgical interventions with dural incision. Aesculap offers three different dura substitutes: Lyoplant® Onlay, Lyoplant® and Neuro-Patch®. The high liquid-tightness of these implants supports the prevention of CSF leakage in neurosurgery. Lyoplant® Onlay is an Onlay dura substitute of bovine origin and enables a fast, easy and versatile application and a reliable treatment. Lyoplant® is a biological suturable dura substitute and Neuro-Patch® is a synthetic suturable dura substitute.1,2,3,4,5,6,7,8,9

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References:

 [1] Clinical trial. Neulen, A et al. Evaluation of efficacy and biocompatibility of a novel semisynthetic collagen matrix as a dural onlay graft in a large animal model. Acta Neurochirurgica. 2011 July 9; 153(11):2241-2250.

[2] Clinical trial. Greifzu F. Clinical Study report LYON study – Assessment of the performance of Lyoplant® Onlay for Duraplasty. 2019.

[3] Clinical trial. Report of a prospective, multi-center, randomized, parallel controlled clinical trial evaluating the effectiveness and safety of the absorbable onlay dura substitute Lyoplant® Onlay in dural repair. 2020.

[4] Expert Report. Bode F. Expert report – Lyoplant® Onlay. 2016.

[5] Expert Report. Nestler U. Expert report – Lyoplant® Onlay. 2015.

[6] Aesculap AG. Rasche A. Results of a Lyoplant® Onlay Evaluation Form. 2015.

[7] Aesculap AG. Test report determination of thickness, test number 2011-RB-62

.[8] Aesculap AG. Test report - Lyoplant® Onlay 180° Folding Test. 2011.

[9] Aesculap AG. Technical data Lyoplant® Onlay. 2011.